Dare you try The Substance at home?

One of 2024's finest makes it to HE

James Whittington
Monday, March 3, 2025

MUBI, the global film distributor, streaming service and production company, has announced that Coralie Fargeat’s Cannes, Golden Globe, BAFTA, SAG-AFTRA and Academy Award®-winning electrifying body-horror, The Substance, will be available to buy on DVD, Blu-ray and Ultra HD Blu-ray from 31 March.

The Substance, a Working Title Films production, is written, directed, co-produced and co-edited by Coralie Fargeat (Revenge), and stars Demi Moore (G.I. Jane, A Few Good Men, Indecent Proposal), Margaret Qualley (Once Upon a Time in Hollywood, Maid, Kinds of Kindness, Fosse Verdon), and Dennis Quaid (Far from Heaven, The Rookie, The Day After Tomorrow).

Demi Moore gives a career-best performance as Elisabeth Sparkle, a former A-lister past her prime and suddenly fired from her fitness TV show by repellent studio head Harvey (Dennis Quaid).

She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn – temporarily – as the gorgeous, twenty-something Sue (Margaret Qualley).

The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?

Coralie Fargeat’s multiple award-winning sensation turns toxic beauty culture inside out with a be-careful-what-you-wish-for fable for the ages. Explosive, provocative and twisted, The Substance is one of the most talked-about, thought-provoking and shocking films released last year.

Special Features include:

“Making of” Featurette

Six exclusive art cards (4K UHD and Blu-ray only)